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Usefulness of Amino Acids

1st half 20242nd half 20231st half 2023

1st half 2024

Amino acid Keyword Title
Alanine Sarcopenia Branched-chain amino acids and L-alanine supplementation ameliorate calcium dyshomeostasis in sarcopenia: New insights for nutritional interventions
Kidney protection A combination of generated hydrogen sulfide and nitric oxide activity has a potentiated protectant effect against cisplatin induced nephrotoxicity
Enteral nutrition Exploring the impact of arginine-supplemented immunonutrition on length of stay in the intensive care unit: A retrospective cross-sectional analysis
Diabetic skin complications Short-Term l-arginine Treatment Mitigates Early Damage of Dermal Collagen Induced by Diabetes
Improved pregnancy outcomes Applications of L-Arginine in Pregnancy and Beyond: An Emerging Pharmacogenomic Approach
Tooth sensitivity Evaluation and comparison of the effects of a new paste containing 8% L-Arginine and CaCO3 plus KNO3 on dentinal tubules occlusion and dental sensitivity: a randomized, triple blinded clinical trial study
Radiation protection effect Review of the evidence of radioprotective potential of creatine and arginine as dietary supplements
Sickle cell anemia Antioxidant supplementation for sickle cell disease
Bone formation l-arginine promotes angio-osteogenesis to enhance oxidative stress-inhibited bone formation by ameliorating mitophagy
Wound healing The effect of L-Arginine therapy on achilles tendon healing: A histological and biomechanical investigation in an animal model
Improved endurance exercise capacity Arginine Regulates Skeletal Muscle Fiber Type Formation via mTOR Signaling Pathway
Sarcopenia Dietary protein and amino acid intakes for mitigating sarcopenia in humans
Testicular dysfunction Mitigative Effects of l-Arginine and N-Acetyl Cysteine against Cisplatin-Induced Testicular Dysfunction and Toxicity through the Regulation of Antioxidant, Anti-inflammatory, and Antiapoptotic Markers: Role of miR-155 and miR-34c Expression
Erectile dysfunction The Effect of the Combination of Ginseng, Tribulus Terrestris, and L-arginine on the Sexual Performance of Men with Erectile Dysfunction: a randomized, double-blind, parallel, and placebo-controlled clinical trial
Postoperative nutrition Usefulness of Perioperative Nutritional Therapy with the Glutamine/Arginine/Calcium β-Hydroxy-β-Methylbutyrate Product in Esophageal Cancer Surgery: A Single-Center Retrospective Study
Sickle cell anemia Sickle Cell Disease: Current Drug Treatments and Functional Foods with Therapeutic Potential
Testicular protection L-arginine attenuates dichlorvos-induced testicular toxicity in male Wistar rats by suppressing oxidative stress-dependent activation of caspase 3-mediated apoptosis
Alleviation of pesticide effects The use of amino acids and their derivates to mitigate against pesticide-induced toxicity
High carbohydrate-induced hyperlipidemia Regulation of Neuropeptide Y Receptor Gene Expression and Hormone Level in Obese Male Rats Receiving 6-Gingerol and L-Arginine Supplementation
Postoperative immune function recovery Arginine on immune function and post-operative obstructions in colorectal cancer patients: a meta-analysis
Blood pressure, triglycerides Effects of arginine intake during weight training on blood variables
Digestive malignancies Current research and future prospects of immunonutrition in gastrointestinal malignancies
Alzheimer's disease L-arginine mitigates choroid plexus changes in Alzheimer's disease rat model via oxidative/inflammatory burden and behavioral modulation
Branched Chain Amino Acids (BCAA) Muscle damage recovery Attenuating Muscle Damage Biomarkers and Muscle Soreness After an Exercise-Induced Muscle Damage with Branched-Chain Amino Acid (BCAA) Supplementation: A Systematic Review and Meta-analysis with Meta-regression
Muscle protection effect The 8:1:1 Supplementation of Branched-Chain Amino Acids in High-Intensity Training: A Case Study of the Protective Effect on Rhabdomyolysis
Liver cirrhosis, sarcopenia Effect of branched-chain amino acid supplementation and exercise on quadriceps muscle quantity and quality in patients with cirrhosis as assessed by ultrasonography: A randomized controlled trial
Sarcopenia Branched-chain amino acids and L-alanine supplementation ameliorate calcium dyshomeostasis in sarcopenia: New insights for nutritional interventions
Diabetic neuropathic pain Branched-Chain Amino Acids Deficiency Promotes Diabetic Neuropathic Pain Through Upregulating LAT1 and Inhibiting Kv1.2 Channel
Skeletal muscle Amino acids regulating skeletal muscle metabolism: mechanisms of action, physical training dosage recommendations and adverse effects
Mental health Role of Branched and Aromatic Amino Acids, Diet Inflammatory Index, and Anthropometric Indices on Mental Health
Sarcopenia Sarcopenia: Recent Advances for Detection, Progression and Metabolic Alterations along with Therapeutic Targets
Postoperative body composition Effects of branched-chain amino acids on changes in body composition during the recovery period following tonsillectomy
Isoleucine Muscle damage recovery Attenuating Muscle Damage Biomarkers and Muscle Soreness After an Exercise-Induced Muscle Damage with Branched-Chain Amino Acid (BCAA) Supplementation: A Systematic Review and Meta-analysis with Meta-regression
Muscle protective effect The 8:1:1 Supplementation of Branched-Chain Amino Acids in High-Intensity Training: A Case Study of the Protective Effect on Rhabdomyolysis
Liver cirrhosis, sarcopenia Effect of branched-chain amino acid supplementation and exercise on quadriceps muscle quantity and quality in patients with cirrhosis as assessed by ultrasonography: A randomized controlled trial
Sarcopenia Branched-chain amino acids and L-alanine supplementation ameliorate calcium dyshomeostasis in sarcopenia: New insights for nutritional interventions
Diabetic neuropathic pain Branched-Chain Amino Acids Deficiency Promotes Diabetic Neuropathic Pain Through Upregulating LAT1 and Inhibiting Kv1.2 Channel
Sarcopenia Role of Branched and Aromatic Amino Acids, Diet Inflammatory Index, and Anthropometric Indices on Mental Health
Sarcopenia Sarcopenia: Recent Advances for Detection, Progression and Metabolic Alterations along with Therapeutic Targets
Postoperative body composition Effects of branched-chain amino acids on changes in body composition during the recovery period following tonsillectomy
Leucine Muscle damage recovery Attenuating Muscle Damage Biomarkers and Muscle Soreness After an Exercise-Induced Muscle Damage with Branched-Chain Amino Acid (BCAA) Supplementation: A Systematic Review and Meta-analysis with Meta-regression
Muscle protective effect The 8:1:1 Supplementation of Branched-Chain Amino Acids in High-Intensity Training: A Case Study of the Protective Effect on Rhabdomyolysis
Prevention of skeletal muscle dysfunction Leucine Supplementation Prevents the Development of Skeletal Muscle Dysfunction in a Rat Model of HFpEF
Muscle protein synthesis Stimulation of muscle protein synthesis with low-dose amino acid composition in older individuals
Type 1 diabetes Risk predictors of glycaemic control in children and adolescents with type 1 diabetes: A systematic review and meta-analysis
Muscle damage recovery Nutrition for European Elite Fencers: A Practical Tool for Coaches and Athletes
Liver cirrhosis, sarcopenia Effect of branched-chain amino acid supplementation and exercise on quadriceps muscle quantity and quality in patients with cirrhosis as assessed by ultrasonography: A randomized controlled trial
Sarcopenia Branched-chain amino acids and L-alanine supplementation ameliorate calcium dyshomeostasis in sarcopenia: New insights for nutritional interventions
Diabetic neuropathic pain Branched-Chain Amino Acids Deficiency Promotes Diabetic Neuropathic Pain Through Upregulating LAT1 and Inhibiting Kv1.2 Channel
Skeletal muscle Amino acids regulating skeletal muscle metabolism: mechanisms of action, physical training dosage recommendations and adverse effects
Muscle strength after gastric cancer resection The effects of resistance exercise and leucine-enriched essential amino acid supplementation on muscle mass and physical function in post-gastrectomy patients: a pilot randomized controlled trial
Muscle atrophy Nutritional Strategies for Muscle Atrophy: Current Evidence and Underlying Mechanisms
Muscle protein synthesis Impacts of protein quantity and distribution on body composition
Sarcopenia The nutritional support to prevent sarcopenia in the elderly
Sarcopenia Dietary protein and amino acid intakes for mitigating sarcopenia in humans
Muscle protein synthesis Muscle Protein Synthesis in Response to Plant-Based Protein Isolates With and Without Added Leucine Versus Whey Protein in Young Men and Women
Cardiac rehabilitation Effectiveness of Nutritional Guidance Focusing on Leucine Intake During Cardiac Rehabilitation Maintenance
Mental health Role of Branched and Aromatic Amino Acids, Diet Inflammatory Index, and Anthropometric Indices on Mental Health
Sarcopenia Dietary protein and amino acid intakes for mitigating sarcopenia in humans
Sarcopenia Sarcopenia: Recent Advances for Detection, Progression and Metabolic Alterations along with Therapeutic Targets
Postoperative body composition Effects of branched-chain amino acids on changes in body composition during the recovery period following tonsillectomy
Valine Muscle damage recovery Attenuating Muscle Damage Biomarkers and Muscle Soreness After an Exercise-Induced Muscle Damage with Branched-Chain Amino Acid (BCAA) Supplementation: A Systematic Review and Meta-analysis with Meta-regression
Muscle protective effect The 8:1:1 Supplementation of Branched-Chain Amino Acids in High-Intensity Training: A Case Study of the Protective Effect on Rhabdomyolysis
Insomnia Microbiota Metabolite Profiles and Dietary Intake in Older Individuals with Insomnia of Short vs. Normal Sleep Duration
Liver cirrhosis, sarcopenia nia Effect of branched-chain amino acid supplementation and exercise on quadriceps muscle quantity and quality in patients with cirrhosis as assessed by ultrasonography: A randomized controlled trial
sarcopenia Branched-chain amino acids and L-alanine supplementation ameliorate calcium dyshomeostasis in sarcopenia: New insights for nutritional interventions
diabetic neuropathic pain Branched-Chain Amino Acids Deficiency Promotes Diabetic Neuropathic Pain Through Upregulating LAT1 and Inhibiting Kv1.2 Channel
mental health Role of Branched and Aromatic Amino Acids, Diet Inflammatory Index, and Anthropometric Indices on Mental Health
sarcopenia Sarcopenia: Recent Advances for Detection, Progression and Metabolic Alterations along with Therapeutic Targets
postoperative body composition Effects of branched-chain amino acids on changes in body composition during the recovery period following tonsillectomy
Citrulline fracture healing Mass Spectrometry Reveals Molecular Effects of Citrulline Supplementation during Bone Fracture Healing in a Rat Model
muscle blood flow L-Citrulline Supplementation Improves Arterial Blood Flow and Muscle Oxygenation during Handgrip Exercise in Hypertensive Postmenopausal Women
anxiety disorder L-Cysteine: A promising nutritional supplement for alleviating anxiety disorders
menopausal obesity A cocktail of histidine, carnosine, cysteine and serine reduces adiposity and improves metabolic health and adipose tissue immunometabolic function in ovariectomized rats
mitigating the effects of pesticides The use of amino acids and their derivates to mitigate against pesticide-induced toxicity
sarcopenia Mitochondria as Nutritional Targets to Maintain Muscle Health and Physical Function During Ageing
anti-obesity Efficacy of L-cysteine in increasing circulatory hydrogen sulfide, nitrite, and 25(OH)VD levels in ZDF rats and in vitro treatment of H2S and NO2 in upregulating VD hydroxylase genes in monocytes
Cystine radiation esophagitis Cystine and theanine for chemoradiotherapy-induced esophagitis in non-small cell lung cancer: a prospective observational study
γ-Aminobuthylic Acid (GABA) neuroinflammation recovery GABA Administration Ameliorates the Toxicity of Doxorubicin on CSF and the Brain of Albino Rats
improving sleep, improving skin condition Effects of a combination of Poria Cocos, Ziziphus spinose, and gamma-aminobutyric acid (GABA) on sleep quality and skin health: A randomized double-blind placebo-controlled clinical trial
type 1 diabetes Gamma-aminobutyric acid for delaying type 1 diabetes mellitus: an update
review Contributions of Gamma-Aminobutyric Acid (GABA) Produced by Lactic Acid Bacteria on Food Quality and Human Health: Current Applications and Future Prospects
Glutamine intestinal mucosa protection L-Glutamine Substantially Improves 5-Fluorouracil-Induced Intestinal Mucositis by Modulating Gut Microbiota and Maintaining the Integrity of the Gut Barrier in Mice
acute kidney injury The Preventive Role of Glutamine Supplementation in Cardiac Surgery-Associated Kidney Injury from Experimental Research to Clinical Practice: A Narrative Review
intestinal mucosa formation Effects of glutamine and omega-3 fatty acids on intestinal neomucosa formation on colon serosa in rats
prevention of muscle weakness Effects of essential amino acid (EAA) and glutamine supplementation on skeletal muscle wasting in acute, subacute, and postacute conditions
abdominal aortic aneurysm Glutamine Protects against Mouse Abdominal Aortic Aneurysm through Modulating VSMC Apoptosis and M1 Macrophage Activation
sarcopenia Dietary protein and amino acid intakes for mitigating sarcopenia in humans
sickle cell anemia Sickle Cell Disease: Current Drug Treatments and Functional Foods with Therapeutic Potential
sickle cell anemia A pharmacokinetic-pharmacodynamic analysis of l-glutamine for the treatment of sickle cell disease: Implications for understanding the mechanism of action and evaluating response to therapy
sickle cell anemia Safety and efficacy of L-Glutamine in reducing the frequency of acute complications among patients with sickle cell disease: A randomized controlled study
postoperative recovery Perioperative Glutamine Supplementation May Restore Atrophy of Psoas Muscles in Gastric Adenocarcinoma Patients Undergoing Gastrectomy
skeletal muscle Amino acids regulating skeletal muscle metabolism: mechanisms of action, physical training dosage recommendations and adverse effects
postoperative nutrition Usefulness of Perioperative Nutritional Therapy with the Glutamine/Arginine/Calcium β-Hydroxy-β-Methylbutyrate Product in Esophageal Cancer Surgery: A Single-Center Retrospective Study
digestive malignant tumors Current research and future prospects of immunonutrition in gastrointestinal malignancies
Glycine mitigating the effects of pesticides The use of amino acids and their derivates to mitigate against pesticide-induced toxicity
sarcopenia Dietary protein and amino acid intakes for mitigating sarcopenia in humans
sarcopenia Mitochondria as Nutritional Targets to Maintain Muscle Health and Physical Function During Ageing
hypertension, hyperlipidemia, hypertension Obesity Association between dietary glycine intake and the prevalence of hypertension, hyperlipidemia, overweight or obesity in rural northern China: a cross-sectional study
hypertension, hyperlipidemia The inverse associations of glycine and histidine in diet with hyperlipidemia and hypertension
Sarcopenia Dietary protein and amino acid intakes for mitigating sarcopenia in humans
Histidine Type 2 diabetes Oral histidine affects gut microbiota and MAIT cells improving glycemic control in type 2 diabetes patients
Hypertension, hyperlipidemia The inverse associations of glycine and histidine in diet with hyperlipidemia and hypertension
Menopausal obesity A cocktail of histidine, carnosine, cysteine and serine reduces adiposity and improves metabolic health and adipose tissue immunometabolic function in ovariectomized rats
Lysine Salt-sensitive hypertension Lysine and salt-sensitive hypertension
Phenylalanine Insomnia Microbiota Metabolite Profiles and Dietary Intake in Older Individuals with Insomnia of Short vs. Normal Sleep Duration
Theanine Liver protection The Protective Effects of L-Theanine against Epigallocatechin Gallate-Induced Acute Liver Injury in Mice
Insomnia in cancer patients Comparison Between Efficacy of Oral Melatonin and Oral L-theanine in Improving Sleep in Cancer Patients Suffering From Insomnia: A Randomised Double-blinded Placebo-controlled Study
Alcoholic fatty liver Hepatoprotective effects and mechanisms of l-theanine and epigallocatechin gallate combined intervention in alcoholic fatty liver rats
Heat stress-related reproductive dysfunction Protective effects of L-theanine and dihydromyricetin on reproductive function in male mice under heat stress
Cardioprotection L-theanine alleviates myocardial ischemia/reperfusion injury by suppressing oxidative stress and apoptosis through activation of the JAK2/STAT3 pathway in mice
Prevention of cognitive dysfunction Effect of Dietary L-Theanine on Protein Expression in the Hippocampus of Senescence-Accelerated Mice (SAMP8)
Sleep improvement Dietary supplementation with Lactium and L-theanine alleviates sleep disturbance in adults: a double-blind, randomized, placebo-controlled clinical study
Visual attention improvement Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study
Cognitive function Improvement of both human and animal memory by synergy between fructooligosaccharide and L-theanine function establishing a safe and effective food supplement
Cognitive ability Impact of L-theanine and L-tyrosine on markers of stress and cognitive performance in response to a virtual reality based active shooter training drill
Sleep improvement Matcha Does Not Affect Electroencephalography during Sleep but May Enhance Mental Well-Being: A Randomized Placebo-Controlled Clinical Trial
Obesity-related syndrome L-Theanine Ameliorates Obesity-Related Complications Induced by High-Fat Diet in Mice: Insights from Transcriptomics and Metabolomics
Tryptophan Inflammatory bowel disease (IBD) Immunoregulatory Effects of Elemental Diet and Its Ingredient, Tryptophan, via Activation of the Aryl Hydrocarbon Receptor in Mice
Functional constipation in the elderly A Low FODMAP Diet Supplemented with L-Tryptophan Reduces the Symptoms of Functional Constipation in Elderly Patients
Small intestinal bacterial overgrowth (SIBO) The importance of food quality, gut motility, and microbiome in SIBO development and treatment
Obstructive defecation syndrome (ODS) Results of medical treatment with psyllium, lactobacillus, and tryptophan (Plurilac® Trio) in obstructive defecation syndrome
Suppression of neuroinflammation Aspartame-induced cognitive dysfunction: Unveiling role of microglia-mediated neuroinflammation and molecular remediation
Postpartum Dietary supplement for mood symptoms in early postpartum: a double-blind randomized placebo controlled trial
Temporomandibular joint disorder The role of nutraceuticals in the management of temporomandibular disorders
Migraine The Brain, the Eating Plate, and the Gut Microbiome: Partners in Migraine Pathogenesis
Sleep improvement Sleep Patterns and Tryptophan Consumption among Students at Spanish Universities: The Unihcos Project
Oxidative damage A comparison of the potential of melatonin and tryptophan to ameliorate CCl4-induced hepatic and renal toxicity in Wistar rats
Tyrosine Insomnia Microbiota Metabolite Profiles and Dietary Intake in Older Individuals with Insomnia of Short vs. Normal Sleep Duration
Exercise performance Acute effects of multi-ingredient pre-workout dietary supplement on anaerobic performance in untrained men: a randomized, crossover, single blind study
Postpartum Dietary supplement for mood symptoms in early postpartum: a double-blind randomized placebo controlled trial
Cognitive ability Impact of L-theanine and L-tyrosine on markers of stress and cognitive performance in response to a virtual reality based active shooter training drill
Other Obesity Association of quality and quantity of macronutrients intake with obesity, new anthropometric indices, lipid accumulation, and blood lipid risk index in Tehranian women

2nd half 2023

Amino acid Keyword Title
Arginine liver protection Quercetin and L-Arginine Ameliorated the Deleterious Effects of Copper Oxide Nanoparticles on the Liver of Mice Through Anti-inflammatory and Anti-apoptotic Pathways
erectile dysfunction Efficacy of L-arginine and Pycnogenol ® in the treatment of male erectile dysfunction: a systematic review and meta-analysis
ovarian function L-arginine supplementation attenuates ovarian oxidative stress in female rats subjected to chronic intermittent hypoxia
muscle Arginine and Lysine Supplementation Potentiates the Beneficial β-Hydroxy ß-Methyl Butyrate (HMB) Effects on Skeletal Muscle in a Rat Model of Diabetes
Oral care Arginine: A New Paradigm in Preventive Oral Care
leg strength Isolated but not combined ergogenic effects of caffeine and L-arginine during an isokinetic knee extension
Alzheimer's dementia Effects of exercise training and L-arginine loaded chitosan nanoparticles on hippocampus histopathology, β-secretase enzyme function, APP, Tau, Iba1and APOE-4 mRNA in aging rats
diabetic muscle atrophy Impact of L-arginine on diabetes-induced neuropathy and myopathy: Roles of PAI-1, Irisin, oxidative stress, NF-κβ, autophagy and microRNA-29a
hypoxia L-arginine supplementation abrogates hypoxia-induced virulence of Staphylococcus aureus in a murine diabetic pressure wound model
pulmonary fibrosis L-arginine mitigates bleomycin-induced pulmonary fibrosis in rats through regulation of HO-1/PPAR-γ/β-catenin axis
BCAA progressive chronic liver disease Use of Branched-Chain Amino Acids as a Potential Treatment for Improving Nutrition-Related Outcomes in Advanced Chronic Liver Disease
liver regeneration Liver regeneration after hepatectomy is significantly suppressed in a muscular atrophy mouse model
insulin resistance High-protein diet with excess leucine prevents inactivity-induced insulin resistance in women
Reduce fatigue The Influence of Branched-Chain Amino Acid Supplementation on Fatigue and Tryptophan Metabolism After Acute and Chronic Exercise in Older Adults: Protocol for a Pilot Randomized Controlled Trial - PubMed (nih.gov)
parkinson's disease Metabolomic analysis of serum short-chain fatty acid concentrations in a mouse of MPTP-induced Parkinson's disease after dietary supplementation with branched-chain amino acids
Post-exercise cognitive function Essential amino acid supplements ingestion has a positive effect on executive function after moderate-intensity aerobic exercise
Liver cancer surgery prognosis Effect of perioperative branched chain amino acids supplementation in liver cancer patients undergoing surgical intervention: A systematic review
Post-exercise blood sugar level Acute consumption of a branched chain amino acid and vitamin B-6 containing sports drink does not improve multiple sprint exercise performance, but increases post-exercise blood glucose
heart failure Branched chain amino acids metabolism in heart failure
wound healing A Pilot Study of Nutritional Supplementation in Soft Tissue Sarcoma Patients
Muscle pain, muscle damage after exercise Branched-Chain Amino Acids Supplementation and Post-Exercise Recovery: An Overview of Systematic Reviews
traumatic brain injury Head Injury Treatment with HEalthy and Advanced Dietary Supplements (HIT HEADS): A pilot randomized controlled trial of the tolerability, safety, and efficacy of branched chain amino acids (BCAAs) in the treatment of concussion in adolescents and young adults
Citrulline Muscle damage prevention Dose-response effect of L-citrulline on skeletal muscle damage after acute eccentric exercise: an in vivo study in mice
Diabetes Anti-obesity and anti-diabetic effects of L-citrulline are sex-dependent
intestinal inflammation Oral post-treatment supplementation with a combination of glutamine, citrulline, and antioxidant vitamins additively mitigates jejunal damage, oxidative stress, and inflammation in rats with intestinal ischemia and reperfusion
Exercise capacity Impact of a short-term nitrate and citrulline co-supplementation on sport performance in elite rowers: a randomized, double-blind, placebo-controlled crossover trial
high blood pressure Perinatal use of citrulline rescues hypertension in adult male offspring born to pregnant uremic rats
Iron overload intestinal dysfunction L-Citrulline ameliorates iron metabolism and mitochondrial quality control via activating AMPK pathway in intestine and improves microbiota in mice with Iron overload
Cysteine oxidative stress, Alzheimer's disease Alzheimer's Disease: A Review of Pathology, Current Treatments, and the Potential Therapeutic Effect of Decreasing Oxidative Stress by Combined Vitamin D and L-Cysteine Supplementation
alcoholic liver damage Combination of Cysteine and Glutathione Prevents Ethanol-Induced Hangover and Liver Damage by Modulation of Nrf2 Signaling in HepG2 Cells and Mice
GABA Obesity risk reduction High Gamma-Aminobutyric Acid (GABA) Oolong Tea Alleviates High-Fat Diet-Induced Metabolic Disorders in Mice
anti aging Beneficial effect of GABA-rich fermented milk whey on nervous system and intestinal microenvironment of aging mice induced by D-galactose
osteoarthritis Gut-joint axis: Oral Probiotic ameliorates Osteoarthritis
obesity Anti-Obesity Effects of GABA in C57BL/6J Mice with High-Fat Diet-Induced Obesity and 3T3-L1 Adipocytes
Exercise capacity Impact of a short-term nitrate and citrulline co-supplementation on sport performance in elite rowers: a randomized, double-blind, placebo-controlled crossover trial
high blood pressure Perinatal use of citrulline rescues hypertension in adult male offspring born to pregnant uremic rats
ischemic heart disease Prophylactic Supplementation with Lactobacillus Reuteri or Its Metabolite GABA Protects Against Acute Ischemic Cardiac Injury
anti stress Gamma-Aminobutyric Acid in Rice Bran Extract Exerts Antistress Effects in Mouse Models with Depressive-Like Behaviors
Glutamine sickle cell disease Long-Term L-Glutamine Treatment Reduces Hemolysis without Ameliorating Hepatic Vaso-Occlusion and Liver Fibrosis in a Mouse Model of Sickle Cell Disease
Renal glomerular damage L-glutamine supplementation reduced morphological damage in the renal glomerulus of rats with Walker-256 tumor
Non-alcoholic fatty liver disease Glutamine Ameliorates Liver Steatosis via Regulation of Glycolipid Metabolism and Gut Microbiota in High-Fat Diet-Induced Obese Mice
Improve nutrition, improve immunity Clinical Study of Glutamine Combined with Early Enteral Nutrition Support on Nutritional Status of Gastric Cancer Patients Undergoing Neoadjuvant Chemotherapy
muscle atrophy Oral glutamine supplementation relieves muscle loss in immobilized rats, altering p38MAPK and FOXO3a signaling pathways
sickle cell anemia Real-world observational study on the long-term effect of L-glutamine treatment on renal parameters of adult and pediatric patients with sickle cell disease
Motor immune depression Supplementation of L-glutamine enhanced mucosal immunity and improved hormonal status of combat-sport athletes
depression, cognitive function The Role of Glutamine Homeostasis in Emotional and Cognitive Functions
oral mucositis Oral glutamine: Is there a role in the amelioration of radiation-induced mucositis? A prospective case-control study at a tertiary care centre in North India
intestinal inflammation Oral post-treatment supplementation with a combination of glutamine, citrulline, and antioxidant vitamins additively mitigates jejunal damage, oxidative stress, and inflammation in rats with intestinal ischemia and reperfusion
Metabolic abnormality-related fatty liver (MAFLD) Glutamine prevents high-fat diet-induced hepatic lipid accumulation in mice by modulating lipolysis and oxidative stress
cancer Glutamine Supplementation as an Anticancer Strategy: A Potential Therapeutic Alternative to the Convention
oral mucositis Clinical and biochemical assessment of the effect of glutamine in management of radiation induced oral mucositis in patients with head and neck cancer: Randomized controlled clinical trial
Glycine sleep improvement Collagen peptide supplementation before bedtime reduces sleep fragmentation and improves cognitive function in physically active males with sleep complaints
type 1 diabetes Harnessing the benefits of glycine supplementation for improved pancreatic microcirculation in type 1 diabetes mellitus
liver damage Boron Facilitates Amelioration of Hepatic Injury by the Osmolyte Glycine and Resolves Injury by Improving the Tissue Redox Homeostasis
Isoleucine Body composition, muscle mass Dietary Intake of Protein and Essential Amino Acids for Sustainable Muscle Development in Elite Male Athletes
liver regeneration Liver regeneration after hepatectomy is significantly suppressed in a muscular atrophy mouse model
insulin resistance High-protein diet with excess leucine prevents inactivity-induced insulin resistance in women
Reduce fatigue The Influence of Branched-Chain Amino Acid Supplementation on Fatigue and Tryptophan Metabolism After Acute and Chronic Exercise in Older Adults: Protocol for a Pilot Randomized Controlled Trial - PubMed (nih.gov)
heart failure Branched chain amino acids metabolism in heart failure
wound healing A Pilot Study of Nutritional Supplementation in Soft Tissue Sarcoma Patients
Muscle pain, muscle damage after exercise Branched-Chain Amino Acids Supplementation and Post-Exercise Recovery: An Overview of Systematic Reviews
Leucine sarcopenia Dietary leucine supplementation restores T-cell mitochondrial respiration and regulates T-lineage differentiation in denervation-induced sarcopenic mice
liver regeneration Liver regeneration after hepatectomy is significantly suppressed in a muscular atrophy mouse model
insulin resistance High-protein diet with excess leucine prevents inactivity-induced insulin resistance in women
Reduce fatigue The Influence of Branched-Chain Amino Acid Supplementation on Fatigue and Tryptophan Metabolism After Acute and Chronic Exercise in Older Adults: Protocol for a Pilot Randomized Controlled Trial - PubMed (nih.gov)
metabolic syndrome The impact of leucine supplementation on body composition and glucose tolerance following energy restriction: an 8-week RCT in adults at risk of the metabolic syndrome
obesity Research progress in the role and mechanism of Leucine in regulating animal growth and development
heart failure Branched chain amino acids metabolism in heart failure
wound healing A Pilot Study of Nutritional Supplementation in Soft Tissue Sarcoma Patients
Muscle pain, muscle damage after exercise Branched-Chain Amino Acids Supplementation and Post-Exercise Recovery: An Overview of Systematic Reviews
muscle protein synthesis Tyrosine Is a Booster of Leucine-Induced Muscle Anabolic Response
cytokine syndrome Leucine alleviates cytokine storm syndrome by regulating macrophage polarization via the mTORC1/LXRα signaling pathway
Lysine muscle Arginine and Lysine Supplementation Potentiates the Beneficial β-Hydroxy ß-Methyl Butyrate (HMB) Effects on Skeletal Muscle in a Rat Model of Diabetes
Ornithine hepatic encephalopathy Efficacy of L-ornithine L-aspartate for minimal hepatic encephalopathy in patients with cirrhosis: A meta-analysis of randomized controlled trials
Theanine Motor and cognitive performance Effect of single or combined caffeine and L-Theanine supplementation on shooting and cognitive performance in elite curling athletes: a double-blind, placebo-controlled study
heat shock L-Theanine alleviates heat stress through modulation of gut microbiota and immunity
intestinal protection The protective effect of L-theanine on the intestinal barrier in heat-stressed organisms
Obesity-induced enterocolitis l-Theanine Prevents Colonic Damage via NF-κB/MAPK Signaling Pathways Induced by a High-Fat Diet in Rats
Tryptophan Menopause Improvement in menopausal symptoms with a nutritional product containing evening primrose oil, hop extract, saffron, tryptophan, vitamins B6, D3, K2, B12, and B9
sleep [Properties of milk in sleep induction]
ulcerative colitis Dietary L-Tryptophan consumption determines the number of colonic regulatory T cells and susceptibility to colitis via GPR15
sleep improvement Overview of the impact of sleep monitoring on optimal performance, immune system function and injury risk reduction in athletes: A narrative review
non-alcoholic fatty liver Tryptophan Prevents the Development of Non-Alcoholic Fatty Liver Disease
pancreatic cancer Tryptophan intake and pancreatic cancer: findings from a case-control study
Trp metabolism Recent Advances in Current Uptake Situation, Metabolic and Nutritional Characteristics, Health, and Safety of Dietary Tryptophan
Tyrosine muscle protein synthesis Tyrosine Is a Booster of Leucine-Induced Muscle Anabolic Response
Valine liver regeneration Liver regeneration after hepatectomy is significantly suppressed in a muscular atrophy mouse model
insulin resistance High-protein diet with excess leucine prevents inactivity-induced insulin resistance in women
Reduce fatigue The Influence of Branched-Chain Amino Acid Supplementation on Fatigue and Tryptophan Metabolism After Acute and Chronic Exercise in Older Adults: Protocol for a Pilot Randomized Controlled Trial - PubMed (nih.gov)
functional dyspepsia Associations among the Duodenal Ecosystem, Gut Microbiota, and Nutrient Intake in Functional Dyspepsia
heart failure Branched chain amino acids metabolism in heart failure
nutrition A Pilot Study of Nutritional Supplementation in Soft Tissue Sarcoma Patients
Muscle pain, muscle damage after exercise Branched-Chain Amino Acids Supplementation and Post-Exercise Recovery: An Overview of Systematic Reviews
Other muscle protein synthesis International Society of Sports Nutrition Position Stand: Effects of essential amino acid supplementation on exercise and performance
stroke Dietary amino acids and risk of stroke subtypes: a prospective analysis of 356,000 participants in seven European countries
obesity Protein and amino acids in obesity: friends or foes?
muscle protein synthesis Protein dose requirements to maximize skeletal muscle protein synthesis after repeated bouts of resistance exercise in young trained women
Elderly protein intake Protein intake affects erythrocyte glutathione synthesis in healthy adults aged ≥60 years in a repeated-measures trial

1st half 2023

Amino acid Keyword Title
Arginine COVID-19 The Effects of arginine-based supplements on fatigue levels following COVID-19 infection: A prospective study in romania
inflammation Effects of glutamine and arginine combination on pro- and anti-inflammatory cytokines
sickle cell disease Effects of l-arginine supplementation in patients with sickle cell disease: A systematic review and meta-analysis of clinical trials
liver Synergistic effect of arginine and Lactobacillus plantarum against potassium dichromate induced-acute liver and kidney injury in rats: Role of iNOS and TLR4/NF-κB signaling pathways
antioxidation Endurance training and L-arginine intake: Their effect on antioxidant indices in the heart muscles of rats
cardiovascular A Critical Review on Vasoactive Nutrients for the Management of Endothelial Dysfunction and Arterial Stiffness in Individuals under Cardiovascular Risk
The effect of L-arginine oral supplementation on the improvement of cardiovascular function and pulmonary artery pressure in patients with major and intermedia β-thalassemia
telogen effluvium Clinical study on the efficacy and tolerability of an oral supplement based on arginine, l-cystine, zinc and B6 vitamin (Cystiphane®) in patients with telogen effluvium
male infertility Micronutrient supplements as antioxidants in improving sperm quality and reducing DNA fragmentation
diabetes L-Arginine in diabetes: clinical and preclinical evidence
Cannabinoid receptor 2 (CB2) agonists and L-arginine ameliorate diabetic nephropathy in rats by suppressing inflammation and fibrosis through NF-κβ pathway
urea cycle Citrulline in the management of patients with urea cycle disorders
cerebral palsy Nutritional Support System (Nss) as a New Therapeutic Strategy for Cerebral Palsy
metabolic syndrome Differential benefits of physical training associated or not with L-arginine supplementation in rats with metabolic syndrome: evaluation of cardiovascular, autonomic and metabolic parameters
preeclampsia Pathophysiology of Preeclampsia and L-Arginine/L-Citrulline Supplementation as a Potential Strategy to Improve Birth Outcomes
pregnancy L-Arginine supplementation in pregnancy: a systematic review of maternal and fetal outcomes
BCAA exercise The Effect of Acute Pre-Workout Supplement Ingestion on Basketball-Specific Performance of Well-Trained Athletes
Walking exercise through smartphone application plus branched-chain amino acid supplementation benefits skeletal muscle mass and strength in liver cirrhosis: A prospective control trial
Effects of branched chain amino acids, l-citrulline, and alpha-glycerylphosphorylcholine supplementation on exercise performance in trained cyclists: a randomized crossover trial
liver The efficacy of branched-chain amino acid granules to restore phagocytic activity in cirrhosis patients, a randomized controlled trial
Effects of Branched-Chain Amino Acids Supplementation on Patients Undergoing Hepatic Intervention: A Meta-Analysis of Randomized Controlled Trials
muscle Co-Ingestion of Branched-Chain Amino Acids and Carbohydrate Stimulates Myofibrillar Protein Synthesis Following Resistance Exercise in Trained Young Men
Effect and feasibility of the combination of branched chain amino acid and exercise therapy on muscle mass and echo intensity of muscle in orthopedic patients in a convalescent rehabilitation hospital: A crossover trial
Comparison of Protein- or Amino Acid-Based Supplements in the Rehabilitation of Men with Severe Obesity: A Randomized Controlled Pilot Study
[Effects of branched-chain amino acid supplementation on skeletal muscle proteolytic pathways after exercise-induced muscle injury in rats]
The Effects of Branched-Chain Amino Acids on Muscle Protein Synthesis, Muscle Protein Breakdown, and Associated Molecular Signalling Responses in Humans: An Update
sarcopenia The Role of Nutrition in the Treatment of Sarcopenia in Old Patients: From Restoration of Mitochondrial Activity to Improvement of Muscle Performance, a Systematic Review
lipid Dietary intakes of branched-chain amino acids and plasma lipid profiles among filipino women in Korea: the Filipino Women's Diet and Health Study (FiLWHEL)
autism Branched-Chain Amino Acids as Adjunctive-alternative Treatment in Patients with Autism: a pilot study
sleep The relationship between the intake of branched-chain and aromatic amino acids and individuals' sleep quality based on body mass index, gender, and age
obesity The Preventive Effect of Exercise and Oral Branched-Chain Amino Acid Supplementation on Obesity-Induced Brain Changes in Ldlr-/-.Leiden Mice
frailty Community-based exercise and nutritional interventions to improve frailty syndrome among older adults: A quasi-experimental study
Branched-chain amino acids supplementation improves liver frailty index in frail compensated cirrhotic patients: a randomized controlled trial
Citrullin exercise The effects of L-Citrulline and Glutathione on Endurance performance in young adult trained males
Prenatal Exposure to L-Citrulline Has Positive Effects on Reflexive Motor Behavior in Newborn Mice
The Effect of acute pre-workout supplement ingestion on basketball-specific performance of well-trained athletes
Effects of branched chain amino acids, l-citrulline, and alpha-glycerylphosphorylcholine supplementation on exercise performance in trained cyclists: a randomized crossover trial
Effect of Combined Grape Seed Extract and L-Citrulline Supplementation on Hemodynamick Responses to Exercise in Young Males
The Effects of Combined Exercise with Citrulline Supplementation on Body Composition and Lower Limb Function of Overweight Older Adults: A Systematic Review and Meta-Analysis.
endothelial function Combined Citrulline and Glutathione Supplementation Improves Endothelial Function and Blood Pressure Reactivity in Postmenopausal Women
A Critical Review on Vasoactive Nutrients for the Management of Endothelial Dysfunction and Arterial Stiffness in Individuals under Cardiovascular Risk
L-Citrulline Supplementation Attenuates Aortic Pressure and Pressure Waves During Metaboreflex Activation in Postmenopausal Women
preterm infant Enteral L-citrulline supplementation in preterm infants is safe and effective in increasing plasma arginine and citrulline levels-a pilot randomized trial
urea cycle Citrulline in the management of patients with urea cycle disorders
lung L-citrulline attenuates lipopolysaccharide-induced inflammatory lung injury in neonatal rats
sepsis Protective effect of citrulline on the intestinal mucosal barrier of mice during sepsis
preeclampsia Pathophysiology of Preeclampsia and L-Arginine/L-Citrulline Supplementation as a Potential Strategy to Improve Birth Outcomes
Cysteine obesity Dietary cysteine drives body fat loss via FMRFamide signaling in Drosophila and mouse
Cystine cancer Ameliorating effects of cystine and theanine in a cancer cachexia mouse model
The effects of cystine and theanine mixture on the chronic survival rate and tumor incidence of rats after total body X-ray irradiation
GABA sleep Integrating animal experiments, mass spectrometry and network-based approach to reveal the sleep-improving effects of Ziziphi Spinosae Semen and γ-aminobutyric acid mixture
skin The Effect of γ-Aminobutyric Acid Intake on UVB- Induced Skin Damage in Hairless Mice
obesity GABA Prevents Age-Related Sarcopenic Obesity in Mice with High-Fat-Diet-Induced Obesity
review Gamma-aminobutyric acid (GABA): a comprehensive review of dietary sources, enrichment technologies, processing effects, health benefits, and its applications
Glutamine exercise L-Glutamine is better for treatment than prevention in exhaustive exercise
cancer Ameliorating effects of cystine and theanine in a cancer cachexia mouse model
muscle Glutamine supplementation accelerates functional recovery of EDL muscles after injury by modulating the expression of S100 calcium-binding proteins
intestine Glutamine protects intestinal immunity through microbial metabolites rather than microbiota
testis Glutamine Supplementation Attenuates Bisphenol A-Induced Testicular Toxicity in Rats
cognitive impairment Glutamine Supplementation Preserves Glutamatergic Neuronal Activity in the Infralimbic Cortex, Which Delays the Onset of Mild Cognitive Impairment in 3×Tg-AD Female Mice
cerebral palsy Nutritional Support System (Nss) as a New Therapeutic Strategy for Cerebral Palsy
lung Glutamine inhibits inflammation, oxidative stress, and apoptosis and ameliorates hyperoxic lung injury
Glycine inflammation Glycine: The Smallest Anti-Inflammatory Micronutrient
cerebral palsy Nutritional Support System (Nss) as a New Therapeutic Strategy for Cerebral Palsy
aging Glycine and aging: Evidence and mechanisms
Leucine exercise Exploring the impact of exercise and essential amino acid plus cholecalciferol supplementation on physical fitness and body composition in multiple sclerosis: A case study
muscle [The Impact of Nutrition on Muscle Health in Older Individuals]
A focus on leucine in the nutritional regulation of human skeletal muscle metabolism in ageing, exercise and unloading states
The combination of quercetin and leucine synergistically improves grip strength by attenuating muscle atrophy by multiple mechanisms in mice exposed to cisplatin
antioxidation Leucine Supplementation Alleviates Immune and Antioxidant Function Damage in Adult Rats Induced by Early Weaning
sarcopenia Management of Sarcopenia in Primary Care Settings
Leucine-enriched amino acid supplementation and exercise to prevent sarcopenia in patients on hemodialysis: a single-arm pilot study
obesity Leucine supplementation in maternal high-fat diet alleviated adiposity and glucose intolerance of adult mice offspring fed a postweaning high-fat diet
Leucine supplementation ameliorates early life "programming" of obesity in rats
frailty The concept and practical management of frailty in neurology
Impact of exercise and leucine-enriched protein supplementation on physical function, body composition, and inflammation in pre-frail older adults: a quasi-experimental study
stress urinary incontinence A randomized controlled pilot trial to assess the effectiveness of a specially formulated food supplement and pelvic floor muscle training in women with stress-predominant urinary incontinence
Lysine liver L-lysine supplementation attenuates experimental autoimmune hepatitis in a chronic murine model
Phenylalanine cardiovascular Higher dietary intake of aromatic amino acids was associated with lower risk of cardiovascular disease mortality in adult participants in NHANES III
sleep The relationship between the intake of branched-chain and aromatic amino acids and individuals' sleep quality based on body mass index, gender, and age
Theanine cancer Ameliorating effects of cystine and theanine in a cancer cachexia mouse model
sleep Theanine maintains sleep quality in healthy young women by suppressing the increase in caffeine-induced wakefulness after sleep onset
testis Protective Effect of l-Theanine on Cyclophosphamide-Induced Testicular Toxicity in Mic
multiple sclerosis L-Theanine Improves Locomotor Function in a Model of Multiple Sclerosis Mice
How does l-theanine treatment affect the levels of serum and hippocampal BDNF, insulin and adipocytokines in diabetic rats?
diabetes Caution may be required in using l-theanine in diabetes mellitus: A study on the rats
heat stress L-Theanine attenuates heat stress-induced proteotoxicity and alterations in carbohydrate and lipid metabolism via heat shock factor 1
Parkinson's disease L-theanine attenuates LPS-induced motor deficit in experimental rat model of Parkinson's disease: emphasis on mitochondrial activity, neuroinflammation, and neurotransmitters
immunity L-Theanine and Immunity: A Review
major depressive disorder l-theanine adjunct to sertraline for major depressive disorder: A randomized, double-blind, placebo-controlled clinical trial
schizophrenia L-Theanine adjunct to risperidone in the treatment of chronic schizophrenia inpatients: a randomized, double-blind, placebo-controlled clinical trial
Threonine iron A short-term intervention of ingesting iron along with methionine and threonine leads to a higher hemoglobin level than that with iron alone in young healthy women: a randomized, double-blind, parallel-group, comparative study
Tryptophan cardiovascular Higher dietary intake of aromatic amino acids was associated with lower risk of cardiovascular disease mortality in adult participants in NHANES III
sleep The Role of Supplements and Over-the-Counter Products to
Improve Sleep in Children: A Systematic Review
The relationship between the intake of branched-chain and aromatic amino acids and individuals' sleep quality based on body mass index, gender, and age
cerebral palsy Nutritional Support System (Nss) as a New Therapeutic Strategy for Cerebral Palsy
obesity Intestinal ACE2 regulates glucose metabolism in diet-induced obese mice through a novel gut-islet axis mediated by tryptophan
Tyrosine cardiovascular Higher dietary intake of aromatic amino acids was associated with lower risk of cardiovascular disease mortality in adult participants in NHANES III
sleep The relationship between the intake of branched-chain and aromatic amino acids and individuals' sleep quality based on body mass index, gender, and age
Other cancer Dietary Manipulation of Amino Acids for Cancer Therapy
muscle Collagen Protein Ingestion during Recovery from Exercise Does Not Increase Muscle Connective Protein Synthesis Rates
Muscle Protein Synthesis with a Hybrid Dairy and Plant-Based Protein Blend (P4) Is Equal to Whey Protein in a Murine Ageing Model after Fasting
protein quality Perspective: Developing a Nutrient-Based Framework for Protein Quality
obesity Dietary amino acids and anthropometric indices: Tehran Lipid and Glucose Study