| Amino acid |
キーワード |
Keyword |
Title |
| Arginine |
肝臓保護 |
liver protection |
Quercetin and L-Arginine Ameliorated the Deleterious Effects of Copper Oxide Nanoparticles on the Liver of Mice Through Anti-inflammatory and Anti-apoptotic Pathways |
| 勃起不全 |
erectile dysfunction |
Efficacy of L-arginine and Pycnogenol ® in the treatment of male erectile dysfunction: a systematic review and meta-analysis |
| 卵巣機能 |
ovarian function |
L-arginine supplementation attenuates ovarian oxidative stress in female rats subjected to chronic intermittent hypoxia |
| 筋肉 |
muscle |
Arginine and Lysine Supplementation Potentiates the Beneficial β-Hydroxy ß-Methyl Butyrate (HMB) Effects on Skeletal Muscle in a Rat Model of Diabetes |
| 口腔ケア |
Oral care |
Arginine: A New Paradigm in Preventive Oral Care |
| 脚力 |
leg strength |
Isolated but not combined ergogenic effects of caffeine and L-arginine during an isokinetic knee extension |
| アルツハイマー型認知症 |
Alzheimer's dementia |
Effects of exercise training and L-arginine loaded chitosan nanoparticles on hippocampus histopathology, β-secretase enzyme function, APP, Tau, Iba1and APOE-4 mRNA in aging rats |
| 糖尿病性筋萎縮 |
diabetic muscle atrophy |
Impact of L-arginine on diabetes-induced neuropathy and myopathy: Roles of PAI-1, Irisin, oxidative stress, NF-κβ, autophagy and microRNA-29a |
| 低酸素症 |
hypoxia |
L-arginine supplementation abrogates hypoxia-induced virulence of Staphylococcus aureus in a murine diabetic pressure wound model |
| 肺繊維症 |
pulmonary fibrosis |
L-arginine mitigates bleomycin-induced pulmonary fibrosis in rats through regulation of HO-1/PPAR-γ/β-catenin axis |
| BCAA |
進行性慢性肝疾患 |
progressive chronic liver disease |
Use of Branched-Chain Amino Acids as a Potential Treatment for Improving Nutrition-Related Outcomes in Advanced Chronic Liver Disease |
| 肝再生 |
liver regeneration |
Liver regeneration after hepatectomy is significantly suppressed in a muscular atrophy mouse model |
| インスリン抵抗性 |
insulin resistance |
High-protein diet with excess leucine prevents inactivity-induced insulin resistance in women |
| 疲労軽減 |
Reduce fatigue |
The Influence of Branched-Chain Amino Acid Supplementation on Fatigue and Tryptophan Metabolism After Acute and Chronic Exercise in Older Adults: Protocol for a Pilot Randomized Controlled Trial - PubMed (nih.gov) |
| パーキンソン病 |
parkinson's disease |
Metabolomic analysis of serum short-chain fatty acid concentrations in a mouse of MPTP-induced Parkinson's disease after dietary supplementation with branched-chain amino acids |
| 運動後認知機能 |
Post-exercise cognitive function |
Essential amino acid supplements ingestion has a positive effect on executive function after moderate-intensity aerobic exercise |
| 肝臓がん手術予後 |
Liver cancer surgery prognosis |
Effect of perioperative branched chain amino acids supplementation in liver cancer patients undergoing surgical intervention: A systematic review |
| 運動後血糖値 |
Post-exercise blood sugar level |
Acute consumption of a branched chain amino acid and vitamin B-6 containing sports drink does not improve multiple sprint exercise performance, but increases post-exercise blood glucose |
| 心不全 |
heart failure |
Branched chain amino acids metabolism in heart failure |
| 創傷治癒 |
wound healing |
A Pilot Study of Nutritional Supplementation in Soft Tissue Sarcoma Patients |
| 筋肉痛、運動後筋損傷 |
Muscle pain, muscle damage after exercise |
Branched-Chain Amino Acids Supplementation and Post-Exercise Recovery: An Overview of Systematic Reviews |
| 外傷性脳損傷 |
traumatic brain injury |
Head Injury Treatment with HEalthy and Advanced Dietary Supplements (HIT HEADS): A pilot randomized controlled trial of the tolerability, safety, and efficacy of branched chain amino acids (BCAAs) in the treatment of concussion in adolescents and young adults |
| Citrulline |
筋ダメージ予防 |
Muscle damage prevention |
Dose-response effect of L-citrulline on skeletal muscle damage after acute eccentric exercise: an in vivo study in mice |
| 糖尿病 |
Diabetes |
Anti-obesity and anti-diabetic effects of L-citrulline are sex-dependent |
| 腸管炎症 |
intestinal inflammation |
Oral post-treatment supplementation with a combination of glutamine, citrulline, and antioxidant vitamins additively mitigates jejunal damage, oxidative stress, and inflammation in rats with intestinal ischemia and reperfusion |
| 運動能力 |
Exercise capacity |
Impact of a short-term nitrate and citrulline co-supplementation on sport performance in elite rowers: a randomized, double-blind, placebo-controlled crossover trial |
| 高血圧 |
high blood pressure |
Perinatal use of citrulline rescues hypertension in adult male offspring born to pregnant uremic rats |
| 過剰鉄性腸機能障害 |
Iron overload intestinal dysfunction |
L-Citrulline ameliorates iron metabolism and mitochondrial quality control via activating AMPK pathway in intestine and improves microbiota in mice with Iron overload |
| Cysteine |
酸化ストレス、アルツハイマー病 |
oxidative stress, Alzheimer's disease |
Alzheimer's Disease: A Review of Pathology, Current Treatments, and the Potential Therapeutic Effect of Decreasing Oxidative Stress by Combined Vitamin D and L-Cysteine Supplementation |
| アルコール性肝障害 |
alcoholic liver damage |
Combination of Cysteine and Glutathione Prevents Ethanol-Induced Hangover and Liver Damage by Modulation of Nrf2 Signaling in HepG2 Cells and Mice |
| GABA |
肥満リスク低減 |
Obesity risk reduction |
High Gamma-Aminobutyric Acid (GABA) Oolong Tea Alleviates High-Fat Diet-Induced Metabolic Disorders in Mice |
| 抗老化 |
anti aging |
Beneficial effect of GABA-rich fermented milk whey on nervous system and intestinal microenvironment of aging mice induced by D-galactose |
| 変形性関節症 |
osteoarthritis |
Gut-joint axis: Oral Probiotic ameliorates Osteoarthritis |
| 肥満 |
obesity |
Anti-Obesity Effects of GABA in C57BL/6J Mice with High-Fat Diet-Induced Obesity and 3T3-L1 Adipocytes |
| 運動能力 |
Exercise capacity |
Impact of a short-term nitrate and citrulline co-supplementation on sport performance in elite rowers: a randomized, double-blind, placebo-controlled crossover trial |
| 高血圧 |
high blood pressure |
Perinatal use of citrulline rescues hypertension in adult male offspring born to pregnant uremic rats |
| 虚血性心疾患 |
ischemic heart disease |
Prophylactic Supplementation with Lactobacillus Reuteri or Its Metabolite GABA Protects Against Acute Ischemic Cardiac Injury |
| 抗ストレス |
anti stress |
Gamma-Aminobutyric Acid in Rice Bran Extract Exerts Antistress Effects in Mouse Models with Depressive-Like Behaviors |
| Glutamine |
鎌状赤血球症 |
sickle cell disease |
Long-Term L-Glutamine Treatment Reduces Hemolysis without Ameliorating Hepatic Vaso-Occlusion and Liver Fibrosis in a Mouse Model of Sickle Cell Disease |
| 腎糸球体損傷 |
Renal glomerular damage |
L-glutamine supplementation reduced morphological damage in the renal glomerulus of rats with Walker-256 tumor |
| 非アルコール性脂肪性肝疾患 |
Non-alcoholic fatty liver disease |
Glutamine Ameliorates Liver Steatosis via Regulation of Glycolipid Metabolism and Gut Microbiota in High-Fat Diet-Induced Obese Mice |
| 栄養改善、免疫改善 |
Improve nutrition, improve immunity |
Clinical Study of Glutamine Combined with Early Enteral Nutrition Support on Nutritional Status of Gastric Cancer Patients Undergoing Neoadjuvant Chemotherapy |
| 筋委縮 |
muscle atrophy |
Oral glutamine supplementation relieves muscle loss in immobilized rats, altering p38MAPK and FOXO3a signaling pathways |
| 鎌状赤血球貧血症 |
sickle cell anemia |
Real-world observational study on the long-term effect of L-glutamine treatment on renal parameters of adult and pediatric patients with sickle cell disease |
| 運動性免疫低下 |
Motor immune depression |
Supplementation of L-glutamine enhanced mucosal immunity and improved hormonal status of combat-sport athletes |
| うつ、認知機能 |
depression, cognitive function |
The Role of Glutamine Homeostasis in Emotional and Cognitive Functions |
| 口腔粘膜炎 |
oral mucositis |
Oral glutamine: Is there a role in the amelioration of radiation-induced mucositis? A prospective case-control study at a tertiary care centre in North India |
| 腸管炎症 |
intestinal inflammation |
Oral post-treatment supplementation with a combination of glutamine, citrulline, and antioxidant vitamins additively mitigates jejunal damage, oxidative stress, and inflammation in rats with intestinal ischemia and reperfusion |
| 代謝異常関連脂肪肝（MAFLD) |
Metabolic abnormality-related fatty liver (MAFLD) |
Glutamine prevents high-fat diet-induced hepatic lipid accumulation in mice by modulating lipolysis and oxidative stress |
| がん |
cancer |
Glutamine Supplementation as an Anticancer Strategy: A Potential Therapeutic Alternative to the Convention |
| 口腔粘膜炎 |
oral mucositis |
Clinical and biochemical assessment of the effect of glutamine in management of radiation induced oral mucositis in patients with head and neck cancer: Randomized controlled clinical trial |
| Glycine |
睡眠改善 |
sleep improvement |
Collagen peptide supplementation before bedtime reduces sleep fragmentation and improves cognitive function in physically active males with sleep complaints |
| １型糖尿病 |
type 1 diabetes |
Harnessing the benefits of glycine supplementation for improved pancreatic microcirculation in type 1 diabetes mellitus |
| 肝障害 |
liver damage |
Boron Facilitates Amelioration of Hepatic Injury by the Osmolyte Glycine and Resolves Injury by Improving the Tissue Redox Homeostasis |
| Isoleucine |
体組成、筋肉量 |
Body composition, muscle mass |
Dietary Intake of Protein and Essential Amino Acids for Sustainable Muscle Development in Elite Male Athletes |
| 肝再生 |
liver regeneration |
Liver regeneration after hepatectomy is significantly suppressed in a muscular atrophy mouse model |
| インスリン抵抗性 |
insulin resistance |
High-protein diet with excess leucine prevents inactivity-induced insulin resistance in women |
| 疲労軽減 |
Reduce fatigue |
The Influence of Branched-Chain Amino Acid Supplementation on Fatigue and Tryptophan Metabolism After Acute and Chronic Exercise in Older Adults: Protocol for a Pilot Randomized Controlled Trial - PubMed (nih.gov) |
| 心不全 |
heart failure |
Branched chain amino acids metabolism in heart failure |
| 創傷治癒 |
wound healing |
A Pilot Study of Nutritional Supplementation in Soft Tissue Sarcoma Patients |
| 筋肉痛、運動後筋損傷 |
Muscle pain, muscle damage after exercise |
Branched-Chain Amino Acids Supplementation and Post-Exercise Recovery: An Overview of Systematic Reviews |
| Leucine |
サルコペニア |
sarcopenia |
Dietary leucine supplementation restores T-cell mitochondrial respiration and regulates T-lineage differentiation in denervation-induced sarcopenic mice |
| 肝再生 |
liver regeneration |
Liver regeneration after hepatectomy is significantly suppressed in a muscular atrophy mouse model |
| インスリン抵抗性 |
insulin resistance |
High-protein diet with excess leucine prevents inactivity-induced insulin resistance in women |
| 疲労軽減 |
Reduce fatigue |
The Influence of Branched-Chain Amino Acid Supplementation on Fatigue and Tryptophan Metabolism After Acute and Chronic Exercise in Older Adults: Protocol for a Pilot Randomized Controlled Trial - PubMed (nih.gov) |
| メタボリックシンドローム |
metabolic syndrome |
The impact of leucine supplementation on body composition and glucose tolerance following energy restriction: an 8-week RCT in adults at risk of the metabolic syndrome |
| 肥満 |
obesity |
Research progress in the role and mechanism of Leucine in regulating animal growth and development |
| 心不全 |
heart failure |
Branched chain amino acids metabolism in heart failure |
| 創傷治癒 |
wound healing |
A Pilot Study of Nutritional Supplementation in Soft Tissue Sarcoma Patients |
| 筋肉痛、運動後筋損傷 |
Muscle pain, muscle damage after exercise |
Branched-Chain Amino Acids Supplementation and Post-Exercise Recovery: An Overview of Systematic Reviews |
| 筋タンパク合成 |
muscle protein synthesis |
Tyrosine Is a Booster of Leucine-Induced Muscle Anabolic Response |
| サイトカインシンドローム |
cytokine syndrome |
Leucine alleviates cytokine storm syndrome by regulating macrophage polarization via the mTORC1/LXRα signaling pathway |
| Lysine |
筋肉 |
muscle |
Arginine and Lysine Supplementation Potentiates the Beneficial β-Hydroxy ß-Methyl Butyrate (HMB) Effects on Skeletal Muscle in a Rat Model of Diabetes |
| Ornithine |
肝性脳症 |
hepatic encephalopathy |
Efficacy of L-ornithine L-aspartate for minimal hepatic encephalopathy in patients with cirrhosis: A meta-analysis of randomized controlled trials |
| Theanine |
運動及び認知パフォーマンス |
Motor and cognitive performance |
Effect of single or combined caffeine and L-Theanine supplementation on shooting and cognitive performance in elite curling athletes: a double-blind, placebo-controlled study |
| ヒートショック |
heat shock |
L-Theanine alleviates heat stress through modulation of gut microbiota and immunity |
| 腸管保護 |
intestinal protection |
The protective effect of L-theanine on the intestinal barrier in heat-stressed organisms |
| 肥満誘発性腸炎 |
Obesity-induced enterocolitis |
l-Theanine Prevents Colonic Damage via NF-κB/MAPK Signaling Pathways Induced by a High-Fat Diet in Rats |
| Tryptophan |
更年期障害 |
Menopause |
Improvement in menopausal symptoms with a nutritional product containing evening primrose oil, hop extract, saffron, tryptophan, vitamins B6, D3, K2, B12, and B9 |
| 睡眠 |
sleep |
[Properties of milk in sleep induction] |
| 潰瘍性大腸炎 |
ulcerative colitis |
Dietary L-Tryptophan consumption determines the number of colonic regulatory T cells and susceptibility to colitis via GPR15 |
| 睡眠改善 |
sleep improvement |
Overview of the impact of sleep monitoring on optimal performance, immune system function and injury risk reduction in athletes: A narrative review |
| 非アルコール性脂肪肝 |
non-alcoholic fatty liver |
Tryptophan Prevents the Development of Non-Alcoholic Fatty Liver Disease |
| 膵臓がん |
pancreatic cancer |
Tryptophan intake and pancreatic cancer: findings from a case-control study |
| Trp代謝 |
Trp metabolism |
Recent Advances in Current Uptake Situation, Metabolic and Nutritional Characteristics, Health, and Safety of Dietary Tryptophan |
| Tyrosine |
筋タンパク合成 |
muscle protein synthesis |
Tyrosine Is a Booster of Leucine-Induced Muscle Anabolic Response |
| Valine |
肝再生 |
liver regeneration |
Liver regeneration after hepatectomy is significantly suppressed in a muscular atrophy mouse model |
| インスリン抵抗性 |
insulin resistance |
High-protein diet with excess leucine prevents inactivity-induced insulin resistance in women |
| 疲労軽減 |
Reduce fatigue |
The Influence of Branched-Chain Amino Acid Supplementation on Fatigue and Tryptophan Metabolism After Acute and Chronic Exercise in Older Adults: Protocol for a Pilot Randomized Controlled Trial - PubMed (nih.gov) |
| 機能性ディスペプシア |
functional dyspepsia |
Associations among the Duodenal Ecosystem, Gut Microbiota, and Nutrient Intake in Functional Dyspepsia |
| 心不全 |
heart failure |
Branched chain amino acids metabolism in heart failure |
| 栄養 |
nutrition |
A Pilot Study of Nutritional Supplementation in Soft Tissue Sarcoma Patients |
| 筋肉痛、運動後筋損傷 |
Muscle pain, muscle damage after exercise |
Branched-Chain Amino Acids Supplementation and Post-Exercise Recovery: An Overview of Systematic Reviews |
| Other |
筋タンパク合成 |
muscle protein synthesis |
International Society of Sports Nutrition Position Stand: Effects of essential amino acid supplementation on exercise and performance |
| 脳卒中 |
stroke |
Dietary amino acids and risk of stroke subtypes: a prospective analysis of 356,000 participants in seven European countries |
| 肥満 |
obesity |
Protein and amino acids in obesity: friends or foes? |
| 筋タンパク合成 |
muscle protein synthesis |
Protein dose requirements to maximize skeletal muscle protein synthesis after repeated bouts of resistance exercise in young trained women |
| 高齢者タンパク摂取量 |
Elderly protein intake |
Protein intake affects erythrocyte glutathione synthesis in healthy adults aged ≥60 years in a repeated-measures trial |
