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臨床試験
| Item: Amino acid (AA) |
Reference Information for safety human study | ||
| [L1]: Safety assessment study | [L2] : Safety review | [L3] Case study (short term, one dose, etc) | |
| L-Glutamine | Journal of Parenteral and enteral nutrition (2004) 28(2):65-75, Rathmacher JA, et al. | Regulatory Toxicology and Pharmacology (2008), 50(3):376-399, Shao A, et al. | Nutrients (2020) 12(10):E2953, Ogden HB, et al. |
| L-Arginine | Amino Acids (2018), 50(1):1215-1229, McNeal CJ, et al | The Journal of Nutrition (2016), 146(12): 2652S-2654S, Cynober L, et al. Regulatory Toxicology and Pharmacology (2008), 50(3):376-399, Shao A, et al. |
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| L-Leucine | American Journal of Clinical Nutrition (2012), 96(8):759-767, Elango R, et al. | The Journal of Nutrition (2016), 146(12):2652S-2654S, Cynober L, et al. The Journal of Nutrition (2012), 142(12):2220S-2224S, Pencharz PB, et al. |
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| Glycine (aminoacetic acid) |
Journal of Urban Living and Health Association (2006), 50(1):27-32, Inagawa K, et al. | No review report of safety & clinical trial | |
| L-Methionine | American Journal of Clinical Nutrition (2017) 106(2):675-683, Deutz NEP, et al. | No review report of safety & clinical trial | 1) Nutrition(2002), 21(2):151-156, Krupkova-Meixnerova L, et al. 2) Revista de Investigacion Clinica (2013), 65(4):323-330, Majluf-Cruz A, et al. |
| L-Tryptophan | The Journal of Nutrition (2013), 143(6):859-866, Hiratsuka C, et al. | The Journal of Nutrition (2016), 146(12): 2652S-2654S, Cynober L, et al. | |
| L-Lysine/HCl | No clinical report on safety assessment | Amino Acids (2019), 51(4):647-659, Hayamizu K, et al. | |
| L-Histidine | American Journal of Clinical Nutrition (2020), 112(5): 1358-1367, Gheller ME, et al. | The Journal of Nutrition, Volume 150, Issue Supplement_1, October 2020, Pages 2606S–2608S, Cynober L, et al. | |
| L-Phenylalanine | Nutrients (2021) 13(6): 1976, Miura, et al. | Amino Acids (2021) 53(9):1313-1328, Blachier F, et al. | Diabetes, metabolic Syndrome and Obesity (2018), 11:22-33 |
| Journal of the International Society of Sports Nutrition (2017), 14:34, Ueda K, et al. | |||
| L-Serine | Nutrients (2021) 13(6): 1976, Miura, et al. | Amino Acids (2021) 53(9):1313-1328, Blachier F, et al. | |
| L-Ornithine/HCl | No clinical report on safety assessment | No review report of safety & clinical trial | Nutrition Research (2008), 28(11):738-743 |
| L-Citruline | No clinical report on safety assessment | No review report of safety & clinical trial | British Journal of Nutrition (2008), 99(4):855-862 |
| L-Valine | No clinical report on safety assessment (Valine alone) |
No review report of safety & clinical trial | |
| L-Iosleucine | No clinical report on safety assessment (Valine alone) |
No review report of safety & clinical trial | |
| L-Alanine | No clinical report on safety assessment (L-Alanine alone) |
No review report of safety & clinical trial | |
| D,L-Alanine | No clinical report on safety assessment | No review report of safety & clinical trial | Biological Psychiatry (2006), 59(3):230-234 |
| L-Aspartic Acid | No clinical report on safety assessment | No review report of safety & clinical trial | Metabolism (1989), 38(2):1179-l 182 |
| L-Asparagine | No clinical report on safety assessment | No review report of safety & clinical trial | |
| D,L-Methionine | No clinical report on safety assessment | No review report of safety & clinical trial | |
| L-Cysteine/HCl | No clinical report on safety assessment | No review report of safety & clinical trial | |
| L-Cysteine | No clinical report on safety assessment | No review report of safety & clinical trial | Metabolism (1989), 28(12):1179-1182 |
| L-Cystine | SEIKATSU EISEI (2008), 52(4):229-236 | No review report of safety & clinical trial | |
| L-Proline | No clinical report on safety assessment | No review report of safety & clinical trial | |
| L-Threonine | No clinical report on safety assessment | No review report of safety & clinical trial | Clinical neuropharmacology (1991), 14(5):403-412 |
| Acta Neurologica Scandinavica (1993), 88(5):334-338 | |||
| Neurology (1996), 47(5):1220-1226 | |||
| L-Tyrosine | No clinical report on safety assessment | No review report of safety & clinical trial | Hypertension (1985), 7(4):593-596 |
| The Lancet (1989), 334(8671):1067-1069 | |||
| Aviation, Space and Environmental Medicine (1995), 66(4):313-319 | |||
| Journal of Child Neurology (2008),23(6):609-13 | |||
| L-Hydroxyproline | No clinical report on safety assessment | No clinical report on safety assessment | |
| (last update: 20220401) | |||
